Endo Aesthetics

Qwo Injectable

Collagenase Clostridium Histolyticum Aux (Injectable)

NEWDiscontinued (was $1,800 per treatment kit) USEDNot sold on secondary market FDACleared 2020
Full cost breakdown, financing, and Section 179 →

Last updated: 2026-09-15

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Model, regulatory, and ownership file

Category
Cellulite Treatment
Manufacturer
Endo Aesthetics
Model scope
Qwo Injectable. Catalog model name; exact configuration needs reconciliation.
Regulatory status
Clearance reported; exact record pending. No exact identifier reconciled.
Labeled or intended-use scope
Buttocks (FDA-approved indication)
Configuration
Collagenase Clostridium Histolyticum Aux (Injectable)
Consumables and recurring dependencies
N/A (discontinued)
Service and warranty
N/A
Training
Confirm the current manufacturer or distributor requirement in writing.
Software
Confirm version, subscription, security support, and transfer eligibility in writing.
Used transfer
Verify serial number, title, recall status, service eligibility, software access, training, accessories, and warranty after transfer.
Evidence
Legacy editorial profile; claim-level packet pending. Packet: No dated source packet yet. Access date: unknown.
Limitations
Commercial terms and exact-model provenance remain subject to current source checks.

Practice ownership and buying signals

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EvaluationNo reader benchmark yet
Replacement intentNo reader benchmark yet
SponsorNo sponsor

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Overview

Qwo Injectable is Endo Aesthetics' entry in the cellulite category, built on Collagenase Clostridium Histolyticum Aux (Injectable). The platform treats buttocks (fda-approved indication), with 10 minutes per treatment and a recommended course of 3 sessions 21 days apart. FDA cleared in 2020, it lists in the Discontinued (was $1,800 per treatment kit) range for new units and Not sold on secondary market on the secondary market.

First and only FDA-approved injectable for moderate to severe cellulite in the buttocks of adult women. Enzymatically severs fibrous septa that create cellulite dimples. Discontinued by Endo in 2022 due to supply chain issues and adverse event reports. The mechanism is what separates Qwo Injectable from competitors in the same category. Where it fits in your practice depends on patient demographics, treatment volume, and whether you need a flagship platform or a value-tier alternative.

Qwo Injectable is manufactured by Endo Aesthetics (Malvern, PA, founded 1997). The device benefits from Endo Aesthetics' public market visibility and presence across 40+ countries. Service support, training availability, and parts access vary by region. Practices considering this device should validate dealer presence and technical support coverage in their area before signing a contract.

TREATMENT AREAS

Buttocks (FDA-approved indication)

TREATMENT TIME

10 minutes per treatment

SESSIONS

3 sessions 21 days apart

PER SESSION

$1,800-$2,500 (historical)

CONSUMABLES/YR

N/A (discontinued)

MAINTENANCE/YR

N/A

Pros & Cons

Pros

  • The only FDA-approved injectable cellulite treatment while active
  • Minimal capital investment (injection-based, no device to buy)
  • Fast 10-minute treatments fit into existing injection clinics
  • Strong scientific mechanism (enzymatic septa release)
  • Covered by physician injection codes and existing clinic workflows

Cons

  • Discontinued by Endo in 2022 and no longer available
  • Bruising reports drove patient complaints and adverse events
  • Supply chain issues made consistent inventory impossible
  • Serves as a cautionary tale about single-source injectables
  • Practices that invested in Qwo branding and training lost that investment

Clinical Evidence

Multiple phase 3 RCTs supporting original FDA approval. Post-market adverse event reports drove the 2022 discontinuation. The published evidence base for Qwo Injectable reflects how long the platform has been in market and how much the manufacturer has invested in clinical research. Devices with FDA clearance dates before 2018 typically have stronger peer-reviewed datasets than newer entrants. For physicians evaluating this device, the questions worth asking are whether the studies used blinded evaluators, what the sample sizes were, and whether the research was independent or manufacturer-funded.

Compare Qwo Injectable's evidence base against the category benchmark. In Qwo Injectable's category, the strongest evidence typically comes from devices that have been on the market for at least five years and have multiple randomized controlled trials with independent funding. Marketing claims from any manufacturer should be cross-checked against PubMed-indexed publications rather than conference posters or white papers. Conference presentations are not equivalent to peer review.

For practices that require strong clinical evidence (academic dermatology, plastic surgery groups with research interests, multi-physician practices that need to defend purchase decisions internally), the evidence profile should be a top-three decision factor. For high-volume cash-pay practices where patient demand drives device selection, brand recognition often matters more than the underlying evidence base. Both approaches are defensible, but they lead to different device selections.

ROI Analysis

Practice ROI for Qwo Injectable depends on three variables: capital cost, per-session revenue, and treatment volume. At a new unit price of Discontinued (was $1,800 per treatment kit), financed over five years at typical equipment rates, the monthly payment runs roughly 2-2.5% of total cost. Per-session revenue at $1,800-$2,500 (historical) means the device needs to fill enough treatment slots monthly to cover the payment, consumables (N/A (discontinued)), maintenance (N/A), and operator labor.

For a practice doing 2-3 treatments per day at the midpoint of the per-session range, Qwo Injectable typically reaches break-even at 12-18 months for the lower end of the new pricing range, or 18-30 months at the high end. Used and refurbished units in the Not sold on secondary market range can cut payback periods in half. The biggest practice mistake is over-projecting treatment volume. Physicians who run their numbers on 4-6 daily treatments rarely hit those targets in year one.

The realistic question is not whether Qwo Injectable can pay back. Most devices in this price range do, eventually. The question is whether your practice can fill the schedule. Practices with existing patient flow in Dermatology, Med Spa have the easiest path. Practices building demand from scratch should plan for 6-12 months of marketing investment before the device pays for itself.

Best For

Historical reference only. Qwo is discontinued and unavailable for purchase. Practices evaluating cellulite treatment should consider Emtone, Cellutone, or mechanical alternatives instead. The fit is strongest for practices that match the device's positioning on price, clinical evidence requirements, and patient throughput expectations. Practices with mismatched economics often regret these purchases within 18 months.

Beyond practice type, Qwo Injectable fits best when the patient base aligns with the device's strengths. For cellulite platforms, this usually means matching device capability to patient demographics, skin type range, and willingness to pay per-session pricing. Practices in markets where patients price-shop heavily need to factor that into device selection. Practices in concierge or luxury markets can charge premium pricing that justifies premium platforms.

Buying Guide

New Qwo Injectable units sell for Discontinued (was $1,800 per treatment kit) from Endo Aesthetics or authorized dealers. Refurbished and used units sell for Not sold on secondary market on the secondary market. The decision between new and used comes down to warranty coverage, software version, included applicators, and consumable allowances. New units typically include a 12-24 month warranty, current software, all applicators, and a starter consumable package. Used units usually carry no warranty, may have outdated software, and require separate consumable purchases.

What to negotiate: applicator quantity (always ask for additional applicators thrown in), consumable starter packs, training and certification fees, extended warranty coverage, marketing materials, and clinical training for additional providers. Endo Aesthetics sales reps typically have 10-15% list price flexibility and far more on bundled deals. End-of-quarter and end-of-year are the strongest negotiation windows. Trade-in programs for older devices can reduce net cost by another 10-20%.

What to watch for: software lock-out fees on used units (some manufacturers disable software on resold devices), per-pulse or per-treatment licensing fees that show up after purchase, consumable price increases over the device life, and service contract terms. Always require a written quote that breaks out hardware, applicators, training, first-year service, and consumables separately. Bundled quotes hide the line items where margins live.

Qwo Cost: Historical Price and Discontinued Status

Qwo cost historically ran $1,800-$2,500 per treatment session, but you cannot buy or receive Qwo today because it was discontinued. The injection was developed for cellulite on the buttocks, and the practical question now is what a physician can offer instead.

Qwo Injectable by Endo Aesthetics used Collagenase Clostridium Histolyticum Aux, an injectable intended to address cellulite. It is no longer an active treatment option, and it is not sold on the secondary market.

What Qwo Cost Before It Was Discontinued

Qwo pricing had two different audiences behind it: the practice buying treatment kits and the patient paying for an appointment. Those figures should not be treated as current pricing. They are historical records from before the product left the market.

Qwo sold for $1,800 per treatment kit before it was discontinued. Source

Historical per-session pricing for patients ran $1,800-$2,500. Source

That range reflects a treatment that required clinical administration and a provider's judgment about the treated area. A patient researching Qwo cost may find old practice pages, old promotional language, or leftover references to coupons. None of that changes availability. There is no current Qwo appointment to book and no legitimate current treatment-kit price to compare.

The historical cost also makes more sense when separated from the question of whether Qwo was the right treatment. Price alone never answered that. Qwo had a narrow approved use, a specific administration protocol, and a clinical history that matters more than a stale price listing.

For the underlying historical pricing record, see the Qwo cost breakdown.

TreatmentTypePer-session priceStatus
QwoInjectable collagenase treatment$1,800-$2,500 historicalDiscontinued
EMTONECellulite device treatment$300-$900Available alternative

Qwo's old patient price was higher than EMTONE's reported per-session range, but these are different treatments with different workflows. The comparison is useful for setting expectations, not for promising an equivalent outcome.

Why You Cannot Get Qwo Anymore

Qwo was discontinued. That is the answer patients need before spending time comparing old quotes, searching for a nearby injector, or looking for a coupon.

The product may still appear in old articles because it generated attention when it entered the cellulite market. That editorial footprint has outlived the commercial product. A physician should not be offering new Qwo treatments, and patients should be skeptical of any listing that implies otherwise.

There is also no secondary market for used Qwo units. That is appropriate for an injectable treatment. A discontinued injectable is not a device somebody can resell, ship, or install in a different practice.

Qwo's discontinuation leaves a gap for people who liked the idea of a targeted cellulite injection. The search for a replacement can get sloppy fast because cellulite treatments vary by technology, treatment area, patient goals, and provider approach. A device-based treatment should be evaluated as its own option, not described as a direct stand-in for Qwo.

Physicians evaluating their treatment menu face a different version of the same problem. Qwo once offered a distinct injectable category. Its absence pushes the conversation back toward available devices and the patient experience those devices can support.

What Physicians Use for Cellulite Instead

EMTONE is one current alternative for practices treating cellulite. It is a device, not an injectable collagenase treatment, which changes the conversation from the start.

EMTONE, a current cellulite device alternative, sells new for $60,000-$95,000 and used for $30,000-$55,000. Source

EMTONE per-session pricing for patients runs $300-$900. Source

That patient-price range makes EMTONE a different commercial model from historical Qwo treatment. It may also be easier for a practice to frame as an available service rather than a discontinued treatment people remember from old coverage.

Patients should ask a provider what technology they use, what area they treat, and what outcome they expect the treatment to address. The label "cellulite treatment" covers a crowded field. It does not tell you whether a treatment uses injections, energy, massage, or another mechanism.

The physician's job is to match the option to the patient in front of them. Some people arrive asking for Qwo because they saw an old article or heard about it from a friend. The productive conversation starts with the fact that Qwo is gone, then moves to what the practice can offer now.

EMTONE is one place to start researching that conversation. See the EMTONE profile for its current device-market record, or browse the wider cellulite device category to compare available approaches.

Qwo's departure also creates a marketing trap for practices. A page built around old Qwo terminology may still attract patients, but it needs to answer the availability question immediately. Sending someone through a long explanation before admitting the product is discontinued is a good way to lose trust.

What Qwo Treatment Involved

Qwo was an injectable treatment from Endo Aesthetics using Collagenase Clostridium Histolyticum Aux. Its approved indication was limited to cellulite on the buttocks.

Qwo was FDA-cleared in 2020 with a buttocks-only approved indication. Source

The treatment protocol was also specific. It was not a broad cosmetic injection that could be casually adapted to any area a patient wanted treated.

The recommended protocol was 3 sessions 21 days apart, about 10 minutes per treatment. Source

That historical protocol explains why Qwo cost is usually discussed per session rather than as a simple one-time price. A patient researching old pricing may see one number for a kit and another for a clinical visit. Those were different parts of the same treatment economics.

The buttocks-only indication matters too. Cellulite concerns can involve several body areas, but Qwo's labeled scope did not turn every cellulite concern into a candidate for the injection. That limitation should remain clear in any historical description of the product.

Qwo is often described as an injectable for cellulite, which is accurate but incomplete. It was a branded product with a constrained indication, a defined protocol, and a supply chain that no longer exists. Those facts belong together.

How to Read Old Qwo Prices and Promotions

Old Qwo price pages can be misleading because they often read like live treatment menus. A historical per-session range may still look current if the page was never updated. A coupon page may still appear in search results even though there is no product behind the promotion.

Treat every Qwo price you find as historical unless it plainly says otherwise. The relevant decision is no longer whether a local provider offers the best Qwo deal. It is whether the provider has a current cellulite-treatment option that fits your goals.

That distinction also helps physicians. A practice can acknowledge the old product and answer patient demand without pretending the treatment remains available. Clear language wins here: Qwo is discontinued; here are the current options we discuss.

A patient asking about old Qwo pricing is often asking a broader question: "What will it cost to address cellulite?" There is no universal answer because treatment choices differ. But a useful provider should explain the technology, expected treatment plan, pricing structure, and the limits of what they can claim.

The historical Qwo record still has value. It helps patients understand what they heard about, why old pricing appears online, and why a current consultation will focus on something else.

The Practical Next Step

If you were looking for Qwo, do not treat its historical price as a shopping benchmark you can still act on. Use it as context.

Ask a qualified physician about currently available cellulite options, including whether EMTONE or another device fits the area and concern you want to address. Ask how the practice prices treatment, what the proposed protocol involves, and why that approach is appropriate for you.

For physicians, the patient-facing message should be just as direct. Qwo is discontinued. The alternative discussion belongs around current treatments, not nostalgia for a product the market no longer has.

The real question is whether a practice can turn an old Qwo inquiry into an honest conversation about the cellulite options it offers now.

Alternatives to review

Use these profiles to build a short list. An alternative listing is not a claim of equivalence or superiority.

EMTONE

EMTONE: Med spas and dermatology practices that already own Emsculpt Neo and want to add targeted cellulite treatment. Practices where patients request cellulite reduct

NEW $60,000-$95,000  ·  USED $30,000-$55,000

Review alternative →

CELLUTONE

CELLUTONE: Med spas already owning Emsculpt Neo or Vanquish ME that want a low-cost cellulite companion device. Practices bundling multi-device treatment packages at premi

NEW $15,000-$28,000  ·  USED $5,000-$12,000

Review alternative →

Frequently Asked Questions

How much does Qwo Injectable cost?

New Qwo Injectable units sell for Discontinued (was $1,800 per treatment kit) from Endo Aesthetics and authorized dealers. Used and refurbished units typically run Not sold on secondary market on the secondary market depending on age, software version, and included applicators. Per-session pricing for treatments is $1,800-$2,500 (historical). Annual consumables run N/A (discontinued) and annual maintenance averages N/A. Practices financing the device should expect monthly payments around 2-2.5% of the total purchase price over a five-year term.

Is Qwo Injectable FDA cleared?

Yes. Qwo Injectable received FDA 510(k) clearance in 2020. The clearance covers the indications listed in the device labeling. Off-label uses are common in clinical practice but should be discussed with patients explicitly. Physicians should verify current clearance status and any updates directly with Endo Aesthetics or via the FDA 510(k) database before making a purchase decision.

What is the clinical evidence behind Qwo Injectable?

Multiple phase 3 RCTs supporting original FDA approval. Post-market adverse event reports drove the 2022 discontinuation. When evaluating clinical evidence, look for blinded evaluator studies, independent funding sources, and peer-reviewed publications rather than manufacturer-funded white papers or conference posters. Evidence quality varies widely between devices in the same category, even when the marketing materials look similar.

Which specialties use Qwo Injectable?

Qwo Injectable is primarily used by Dermatology, Med Spa, Plastic Surgery. Best fit varies by patient mix and practice economics. Historical reference only. Qwo is discontinued and unavailable for purchase. Practices evaluating cellulite treatment should consider Emtone, Cellutone, or mechanical alternatives instead.

How long does a Qwo Injectable treatment session take?

Each Qwo Injectable treatment session runs 10 minutes per treatment. The recommended protocol is 3 sessions 21 days apart. Total chair time including consultation, setup, treatment, and post-treatment care is typically 1.5-2x the listed treatment time. Practices planning daily treatment volume should use the realistic chair-time number, not just the active treatment minutes.

What are the main pros and cons of Qwo Injectable?

Strengths: The only FDA-approved injectable cellulite treatment while active; Minimal capital investment (injection-based, no device to buy); Fast 10-minute treatments fit into existing injection clinics. Weaknesses: Discontinued by Endo in 2022 and no longer available; Bruising reports drove patient complaints and adverse events; Supply chain issues made consistent inventory impossible. Every device in this category has tradeoffs. The right choice depends on which strengths matter most to your practice and which weaknesses you can tolerate.

What does Qwo Injectable cost to operate annually?

Annual operating costs for Qwo Injectable include consumables (N/A (discontinued)), maintenance and service (N/A), and operator labor. Practices doing high treatment volumes should also budget for additional applicator wear and replacement. Total annual operating cost typically runs 5-15% of the original purchase price, with consumables driving most of the variability between low and high estimates.

Who manufactures Qwo Injectable and how stable is the company?

Qwo Injectable is manufactured by Endo Aesthetics, headquartered in Malvern, PA and founded in 1997. The company is publicly traded under ticker ENDP and operates in 40+ countries. Standalone annual revenue is not separately reported (Part of Endo International ($2B+)). Manufacturer financial stability matters because it affects warranty support, parts availability, and long-term software updates. Physicians making capital purchases should always check the manufacturer's recent financial trajectory before committing.

What does Qwo Injectable cost in 2026?

As of April 2026, Qwo Injectable new unit pricing is Discontinued (was $1,800 per treatment kit) from Endo Aesthetics and authorized dealers. Refurbished and used unit pricing typically runs Not sold on secondary market on the secondary market. Per-session treatment pricing for patient billing is $1,800-$2,500 (historical). Pricing has held relatively stable through 2025-2026 across the cellulite category, though specific applicator and consumable pricing varies. Practices should request current quotes directly from Endo Aesthetics sales for the most accurate 2026 pricing because list price varies meaningfully by region, configuration, and trade-in deals.

How does Qwo Injectable compare to other cellulite devices in 2026?

In the 2026 cellulite category, Qwo Injectable competes primarily with the other devices reviewed on DevicePulse: emtone, cellutone. The differentiation comes down to clinical evidence depth, treatment time per session, applicator versatility, and total cost of ownership over a 5-year period. Most practices choose between 2-3 finalists based on specialty mix, patient volume, and existing equipment compatibility. Run a side-by-side total cost of ownership analysis before committing to a capital purchase.

What is the Qwo Injectable treatment protocol and recommended session count?

The Qwo Injectable recommended treatment protocol is 3 sessions 21 days apart, with each session running 10 minutes per treatment. Total treatment plan duration depends on the indication and patient response. For patient pricing and ROI calculations, multiply per-session pricing ($1,800-$2,500 (historical)) by the recommended session count to get the patient-facing treatment course cost. Practices typically build the treatment plan into a package price rather than billing per session, which improves patient retention through the full protocol.

What's the latest news and updates for Qwo Injectable in 2026?

As of April 2026, Qwo Injectable continues commercial availability from Endo Aesthetics. Recent industry updates relevant to the device include manufacturer financial disclosures, new clinical evidence publications, software updates, and FDA labeling changes. Endo Aesthetics publishes quarterly financial results that inform the long-term outlook for Qwo Injectable support and continued investment. Check the manufacturer's investor relations page or press releases for the most current operational status.